Cardiac function in patients with Fukuyama-type congenital muscular dystrophy

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Brain MR in Fukuyama congenital muscular dystrophy.

PURPOSE To determine the MR characteristics of brain abnormalities in Fukuyama congenital muscular dystrophy (FCMD). METHODS We reviewed 30 MR examinations of 21 patients with FCMD to assess cerebral and cerebellar cortical dysplasia, white matter changes, and miscellaneous abnormalities. RESULTS On MR images, all patients had thick and bumpy cortices with shallow sulci corresponding to pol...

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Fukuyama congenital muscular dystrophy (FCMD) is the most common congenital muscular dystrophy in Japan and there are isolated reports of non-Japanese patients with FCMD. We report an Indian patient with congenital muscular dystrophy and characteristic radiological findings similar to those with FCMD.

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Novel mutations and genotype-phenotype relationships in 107 families with Fukuyama-type congenital muscular dystrophy (FCMD).

Fukuyama-type congenital muscular dystrophy (FCMD), one of the most common autosomal recessive disorders in the Japanese population, is characterized by congenital muscular dystrophy in combination with cortical dysgenesis (micropolygyria). Recently, we identified, on chromosome 9q31, the gene responsible for FCMD, which encodes a novel 461 amino acid protein which we have termed fukutin. Most ...

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MR Imaging of Fukuyama Congenital Muscular Dystrophy: A Case Report

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Left ventriculoplasty for dilated cardiomyopathy in Fukuyama-type muscular dystrophy.

A 29-year-old man was hospitalized because of heart failure causing dilated cardiomyopathy (DCM). On admission, he had elevated creatinine kinase levels (hyper CKemia) (4283IUl⁻) and false enlargement of bilateral calves. By a muscular biopsy, he was diagnosed as Fukuyama-type muscular dystrophy. Although neuromuscular diseases are often related to cardiomyopathy, reports showing a relation bet...

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ژورنال

عنوان ژورنال: Journal of the American College of Cardiology

سال: 2003

ISSN: 0735-1097

DOI: 10.1016/s0735-1097(03)81792-8